Lorazepam half life10/31/2023 ![]() ![]() Use of benzodiazepines, including lorazepam, may lead to physical and psychological dependence.Īs with all patients on CNS-depressant drugs, patients receiving lorazepam should be warned not to operate dangerous machinery or motor vehicles and that their tolerance for alcohol and other CNS depressants will be diminished. ![]() (See PRECAUTIONS, Clinically Significant Drug Interactions) Use of benzodiazepines, including lorazepam, both used alone and in combination with other CNS depressants may lead to potentially fatal respiratory depression. Lorazepam is not recommended for use in patients with a primary depressive disorder or psychosis. ![]() Pre-existing depression may emerge or worsen during use of benzodiazepines including lorazepam.
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